Osteosarcoma of the larynx
نویسندگان
چکیده
Malignant neoplasms of the larynx are divided into epithelial and non-epithelial. Non-epithelial neoplasms include, among others, mesenchymal chondrosarcomas and osteosarcomas. Few cases of laryngeal osteosarcomas described in the literature were usually treated by surgery without the need to use adjuvant radio- or chemotherapy. Few authors propose the initial application of radiotherapy or high-dose chemotherapy. Our study presents a very rare case of a woman treated due to laryngeal osteosarcoma. We have also presented diagnostic difficulties preceding a decision to perform radical surgery. The patient had been eligible for radical surgical treatment, even though there were no features of malignancy in a histopathological examination of the biopsy material. Complete laryngectomy was carried out without the surgery of the cervical lymphatic system. Laryngeal osteosarcoma was diagnosed based on the postoperative histopathological examination using vimentin and Ki67. The patient remains under the care of the Otolaryngology and Laryngological Oncology Department and Oncology Centre in Bydgoszcz. There were no reports on local recurrence or distant metastases during regular check-ups.
منابع مشابه
Osteosarcoma of the larynx.
Malignant mesenchymal tumors of the larynx constitute 0.3% to 1% of all laryngeal cancers. Of them, osteosarcoma is the rarest. Osteosarcoma of the larynx may be a difficult clinical diagnosis. Pathologic confirmation of osteoid is required for the diagnosis. Treatment is primarily surgical. It is believed that aggressive surgical intervention directed at complete tumor extirpation is the treat...
متن کاملOsteosarcomas of the larynx.
OBJECTIVES/HYPOTHESIS The objective was to review the etiology, presentation, treatment, and prognosis in patients with osteosarcoma of the larynx using an illustrative case example. STUDY DESIGN Case report and literature review. METHODS A case is reported, and a review of all available published cases of osteosarcoma of the larynx is presented. RESULTS Osteosarcoma of the larynx may be ...
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The incidence of laryngeal sarcoma is exceedingly low with osteosarcomas of the larynx being rarer still, comprising less than 1% of all associated malignancies. To date, only 32 cases have been reported since this pathologic entity was first described in 1942. In this article, we discuss the most recent case of laryngeal osteosarcoma in a patient presenting with respiratory distress found to b...
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BACKGROUND We add a new rare illustrative case of osteosarcoma of the larynx to the literature. CASE PRESENTATION The patient (man; 56 years old) first underwent several biopsies, followed in the end by a total laryngectomy. Diagnosis was histological. The patient developed regional and distant metastases and died of disease after 3 months from surgery. CONCLUSION Osteosarcoma of the larynx...
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BACKGROUND Sarcomas of the larynx are uncommon tumors, and osteosarcoma is the rarest. Only 24 cases of osteosarcoma of the larynx have been reported. The only case reported in Asia was from Thailand in 1981. METHODS A 55-year-old male patient was referred to our hospital because of an 8-month history of odynophagia and a gradually enlarging left neck mass. A neck CT scan was performed. A lit...
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